Strain Report - Rat Genome Database

Name: SD- Hamp em2Jfcol -/-
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Strain Registration

General

Strain: SD-Hamp^{em2Jfcol -/-}

Symbol:

SD-Hamp^{em2Jfcol -/-}

Strain:

SD-Hamp^em2-/-

Substrain:

Jfcol

RGD ID:

36174222

Citation ID:

RRID:RRRC_00909

Ontology ID:

RS:0005015

Alleles:

Hamp^em2Jfcol

Also Known As:

RRRC:00909; SD-Hamp^[ em2Jfcol -/-]

Type:

mutant

Available Source:

Rat Resource & Research Center (RRRC)

Description:

Hamp KO, Sprague-Dawley rats were generated by Transposagen Biopharmaceuticals (Lexington, KY). Four different genetically engineered rat lines, each with different sized Hamp deletions (with or without concurrent insertions), were created using TALEN technology. SD-Hamp em2Jfcol -/- (RGD:36174222) is homozygous carrying a 230-bp deletion and a 1-bp insertion between exons 2 & 3 of both rat Hamp alleles.

Genetic Status:

Homozygous

Last Known Status:

Cryopreserved Sperm (as of 2020-07-29)

Research Usage

This rat models hereditary hemochromatosis (Type 2B) in humans. Iron overload research.

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	86,170,926 - 86,172,865	RGD_MAPPER_PIPELINE	mRatBN7.2
Rnor_6.0	1	89,368,021 - 89,369,960	RGD_MAPPER_PIPELINE	Rnor6.0
Rnor_5.0	1	90,523,506 - 90,525,473	RGD_MAPPER_PIPELINE	Rnor5.0
RGSC_v3.4	1	85,978,120 - 85,980,059	RGD_MAPPER_PIPELINE	RGSC3.4

Annotation Click to see Annotation Detail View

References

References - curated

#	Reference Title	Reference Citation
1.	Strains registered by Jennifer Lee from University of Florida	Strains registered by Jennifer Lee from University of Florida

Region

Additional Information

External Database Links

Database	Acc Id	Source(s)
RRRC	RRRC:00909	RGD

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Strain: SD-Hamp em2Jfcol -/-

Strain: SD-Hamp^{em2Jfcol -/-}