Ccdc85c (coiled-coil domain containing 85C)

Gene: Ccdc85c (coiled-coil domain containing 85C) Rattus norvegicus

Analyze

Symbol:

Ccdc85c

Name:

coiled-coil domain containing 85C

RGD ID:

1589818

Description:

Predicted to be involved in cerebral cortex development. Predicted to act upstream of or within several processes, including Notch signaling pathway; establishment of cell polarity; and radial glial cell differentiation. Predicted to be located in adherens junction and apical junction complex. Used to study hydrocephalus. Orthologous to human CCDC85C (coiled-coil domain containing 85C); INTERACTS WITH 3-chloropropane-1,2-diol; atrazine; bisphenol A.

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

coiled-coil domain-containing protein 85C; LOC690965; similar to CG17265-PA

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Allele / Splice:

Ccdc85c^em1Kyo

Genetic Models:

F344-Ccdc85c^em1Kyo

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	132,877,851 - 132,948,744 (-)	NCBI		GRCr8
mRatBN7.2	6	127,113,440 - 127,184,328 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	127,113,442 - 127,184,371 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	6	132,113,806 - 132,183,434 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	6	141,284,186 - 141,353,658 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	132,572,485 - 132,641,431 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	6	124,672,684 - 124,742,377 (-)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

hydrocephalus (IMP,ISS)

INTELLECTUAL DEVELOPMENTAL DISORDER WITH HYPERTELORISM AND DISTINCTIVE FACIES (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

3-chloropropane-1,2-diol (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

caffeine (ISO)

copper atom (ISO)

copper(0) (ISO)

diquat (ISO)

doxorubicin (ISO)

ethanol (ISO)

FR900359 (ISO)

ivermectin (ISO)

PCB138 (ISO)

perfluorononanoic acid (ISO)

resveratrol (ISO)

sodium arsenite (ISO)

tetrachloromethane (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell population proliferation (ISO)

cerebral cortex development (ISO)

establishment of cell polarity (ISO)

establishment of protein localization (ISO)

Notch signaling pathway (ISO)

radial glial cell differentiation (ISO)

Cellular Component

adherens junction (ISO)

apical junction complex (ISO)

Molecular Function

protein binding (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

intracranial hemorrhage (IMP)

premature death (IMP)

References

References - curated

#	Reference Title	Reference Citation
1.	Pathological characteristics of Ccdc85c knockout rats: a rat model of genetic hydrocephalus.	Konishi S, etal., Exp Anim. 2020 Jan 29;69(1):26-33. doi: 10.1538/expanim.19-0005. Epub 2019 Jul 23.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:22056358	PMID:25644709	PMID:34657927

Genomics

Comparative Map Data

Ccdc85c
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	132,877,851 - 132,948,744 (-)	NCBI		GRCr8
mRatBN7.2	6	127,113,440 - 127,184,328 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	127,113,442 - 127,184,371 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	6	132,113,806 - 132,183,434 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	6	141,284,186 - 141,353,658 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	132,572,485 - 132,641,431 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	6	124,672,684 - 124,742,377 (-)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

CCDC85C
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	99,500,190 - 99,604,207 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	99,500,190 - 99,604,207 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	99,966,527 - 100,070,544 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	99,046,540 - 99,140,110 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	14	80,032,485 - 80,125,607 (-)	NCBI		Celera
Cytogenetic Map	14	q32.2	NCBI
HuRef	14	80,161,003 - 80,254,066 (-)	NCBI		HuRef
CHM1_1	14	99,915,361 - 100,008,351 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	14	93,731,756 - 93,835,650 (-)	NCBI		T2T-CHM13v2.0

Ccdc85c
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	108,169,858 - 108,244,111 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	108,169,861 - 108,241,684 (-)	Ensembl		GRCm39 Ensembl
GRCm38	12	108,203,599 - 108,277,852 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	108,203,602 - 108,275,425 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	109,444,555 - 109,513,627 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	108,654,152 - 108,723,483 (-)	NCBI		MGSCv36	mm8
Celera	12	109,446,564 - 109,515,546 (-)	NCBI		Celera
Cytogenetic Map	12	F1	NCBI
cM Map	12	59.23	NCBI

Ccdc85c
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955438	20,853,560 - 20,909,510 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955438	20,851,085 - 20,909,512 (-)	NCBI	ChiLan1.0	ChiLan1.0

CCDC85C
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	100,666,643 - 100,760,232 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	99,883,139 - 99,976,695 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	80,134,889 - 80,229,717 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	99,458,198 - 99,550,546 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

CCDC85C
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	67,930,372 - 68,006,689 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	67,929,555 - 68,004,891 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	67,450,734 - 67,528,156 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	68,214,408 - 68,291,855 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	68,215,298 - 68,292,190 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	67,875,375 - 67,952,761 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	67,941,872 - 68,019,111 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	68,338,989 - 68,416,468 (-)	NCBI		UU_Cfam_GSD_1.0

Ccdc85c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	6,693,763 - 6,765,570 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936604	3,319,799 - 3,388,781 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936604	3,316,898 - 3,388,687 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CCDC85C
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	120,514,491 - 120,597,318 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	120,514,488 - 120,597,409 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	128,124,329 - 128,148,522 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CCDC85C
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	77,470,947 - 77,560,425 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	77,471,048 - 77,560,331 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	64,606,196 - 64,701,019 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ccdc85c
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	4,310,607 - 4,366,209 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	4,310,662 - 4,366,209 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ccdc85c
394 total Variants

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
731173	Uae22	Urinary albumin excretion QTL 22	10.1		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
2290393	Uae37	Urinary albumin excretion QTL 37		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
724536	Uae7	Urinary albumin excretion QTL 7	3.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	72202632	130729475	Rat
1331799	Bp211	Blood pressure QTL 211	3.66407		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	72202632	130919985	Rat
1581550	Pur8	Proteinuria QTL 8			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	72227641	130729205	Rat
1581563	Uae33	Urinary albumin excretion QTL 33			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	72227641	130729205	Rat
738034	Anxrr5	Anxiety related response QTL 5	5.9		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	6	84130881	129130881	Rat
10054138	Gmadr3	Adrenal mass QTL 3	3.68	0.00045	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	6	85140138	130140138	Rat
10054123	Srcrt6	Stress Responsive Cort QTL 6	2.5	0.0043	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	85140138	130140138	Rat
724513	Uae14	Urinary albumin excretion QTL 14	6.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	85311061	133478515	Rat
1300076	Glom8	Glomerulus QTL 8	7	0.000000009	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)	6	86894788	131894788	Rat
2303624	Vencon5	Ventilatory control QTL 5	4.45		respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	6	88047916	133047916	Rat
1331725	Bp212	Blood pressure QTL 212	3.52475		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	93701310	128713626	Rat
61414	Pia3	Pristane induced arthritis QTL 3	4.5		joint integrity trait (VT:0010548)	post-insult time to onset of experimental arthritis (CMO:0001450)	6	94968928	137848904	Rat
12801411	Schws8	Schwannoma susceptibility QTL 8			nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	94968928	139968928	Rat
8552796	Vie3	Viral induced encephalitis QTL 3	2.6		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	6	96833997	140994061	Rat
1358355	Srcrt4	Stress Responsive Cort QTL 4	6.39		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	100364669	140994061	Rat
2313399	Anxrr28	Anxiety related response QTL 28			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	6	100671796	132340886	Rat
1331797	Bp213	Blood pressure QTL 213	3.291		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	104085867	128713626	Rat
71111	Iddm8	Insulin dependent diabetes mellitus QTL 8	1.9	0.002	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	6	105156861	140994061	Rat
4145118	Mcs26	Mammary carcinoma susceptibility QTL 26		0.0001	mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	6	106752656	132339866	Rat
737976	Pia24	Pristane induced arthritis QTL 24			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	6	112636280	140994061	Rat
1298087	Iddm18	Insulin dependent diabetes mellitus QTL 18		0.0001	urine glucose amount (VT:0001758)	percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)	6	116506292	130245370	Rat
1641917	Colcr5	Colorectal carcinoma resistance QTL 5	3.18	0.0009	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	6	122549046	137801795	Rat
2293085	Iddm29	Insulin dependent diabetes mellitus QTL 29	7.66		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	6	122549046	140286318	Rat
61329	Eae9	Experimental allergic encephalomyelitis QTL 9	3.7		body mass (VT:0001259)	change in body weight (CMO:0002045)	6	122549046	140994061	Rat
2312560	Pur20	Proteinuria QTL 20	2.1	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	125628133	137801795	Rat

Genetic Models

This gene Ccdc85c is modified in the following models/strains:

F344-Ccdc85c^em1Kyo

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_006225872	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006240553	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039113371	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039113372	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039113373	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000095434 ⟹ ENSRNOP00000076803

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	127,113,442 - 127,184,371 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000104756 ⟹ ENSRNOP00000093459

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	127,113,442 - 127,184,371 (-)	Ensembl

RefSeq Acc Id:

XM_006240553 ⟹ XP_006240615

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	132,877,851 - 132,948,744 (-)	NCBI
mRatBN7.2	6	127,113,440 - 127,184,327 (-)	NCBI
Rnor_6.0	6	132,113,806 - 132,183,434 (-)	NCBI
Rnor_5.0	6	141,284,186 - 141,353,658 (-)	NCBI

Sequence:

show sequence

ATGGCGAAGCCCCCGGCGGTGGCGGCGGCGGCTGCGGCGGCGGCGTCGGAGGAGCTGAGCCAGG
TGCCGGACGAGGAACTGCTGCGCTGGAGCAAGGAGGAGCTGGCGCGGCGGCTGCGGCGCGCCGA
GGGCGAGAAGGTGGGCCTCATGCTGGAGCACGGCGGCCTGATGCGCGATGTGAACCGGCGGCTG
CAGCAGCACCTGCTGGAGATCCGCGGCCTCAAGGACGTGAACCAGCGGCTGCAGGACGACAATC
AGGAGCTGCGCGAGCTCTGCTGTTTCCACGTCCCCCCGGCCCTGCTGCCCCCGGGGCCGCACAA
GGGTCCGGAGGGCAAGGCCGGTGCCACGCGCCGGTCCCTGGATGACCTGTCAGCGCCGCCGCAC
CACCGAAGCATCCCTAACGGCCTGCACGATCCCTCATCTACCTACATCAGGCCGTTGGAGACCA
AGGTGAAGCTGTTGGATGGTGACAAACTCCCCCCACAGCTGCCCCGCCCCTACGGCCTCCAGAG
AAGCCGGCTCCAGCAGGCAGGCTCTGGAGAGTTCCGGACACTTCGGAAAGGCTTCTCCCCATAC
CATTCGGAATCCCAGCTTGCGTCCCTGCCGCCCTCCTACCAGGAAGTCCTACAGAACGGTCCAG
CCTGCCCTGTACCGGAGCTGCCCTCACCCCCTTCCACCGTCTACAGTTCAGCAGGACAGAAGCC
TGAGGCTGTTGTGCATGCCATGAAGGTTCTGGAAGTACATGAGAACCTTGACCGGCAGCTCCAA
GACAGCTGTGAGGAGGACCTGAGCGAGAAGGAGAAGGCCATCGTTCGAGAGATGTGCAACGTGG
TCTGGAGGAAACTGGGGGACGCTGCCAGCACCAAGCCCTCCATCCGGCAGCACCTGTCTGGTAA
TCAGTTCAAGGGGCCGTTGTAGGGCCATCTCTCCATGGGTGCAGACTGGCCCTGCCTGGAGTCT
GAGGCCTTAGACCTGGCAGAAACTCTGGCCTAGCCACCGTCTTTCTCCGTGGTGAATTGTACAT
AGGACACGGCCCACCCTGGCTGCCCTGGTGTGACACTGACTGCCCAGGCCTCCACCTCCTGCCT
CCCTCACCAGCAAACCTTGGCAAGACAAGAAGCCATGGCCTGCTCGCTGCAGCAAAGTGGCCAG
GCAGCCTGGCTCCCCGTTTGAGCTCCACGTTCCATTAGCAAGAAGCTTCTGAGACTCCAAGCCA
AGGGATTGTCTGGGGAGGTGCCCTGCTCTTGGTAGAAGTCCCTTGACAAGTATTCTAACTGTCC
CTTACACTGGACAGAAGCCACCAGAGCCTCAATTGTGACACGGGTGGCGCTTTCTGCTACCCGG
CCAGAGCCGGGACCCTGGGTCACGGAGCACTGGCTCCCACGTATCCATTGGCTGGCCGGGAGCT
CAGGGTTCCCTGTCACCTGGGGGTTGGTGCCCAGCCGCCCTGATGCCAGCTGCTGCTCACTAAC
ATTCACCCCCTCAGTAGCATCTCCTTGCCTAGGTCAGGCTTAGCCACTTCTTAGGTCTCTCCTG
CCAGGTTTCCTTTTCTGGTTTACAGCAACATAGGAAAAAGCCCTGGAGATGTCCGGGCTGAGCT
CAGCATTCTCAATGGGCAGGTAGAACCGGGCCATTGCCCTGGCTCACTGTCGATGTGACCTCCC
CACCCCCCATGTGCTCTGGGTCACTATGGATGGACCTACAGGAGCCGCCCCTGATGAGTTTTCC
CTGGGAAGGAAGGGGCATGACCTGGTTCTGGCTTTAATCTGCTGTGTGGCCTTCAGCAAGCCAC
TCAGCTTCTCTGGGCTCCCAGCGGTTCCCTTTGGCTTTGCTTACTCTAGAAACCACCCCAGTTT
GGTGGGCCTCTGTCCTCAACAACGGATGAGCTCATGTGGTAACTTACCAGGAACATGCTAGGCC
AGCCTGTCTGTCATGCTGTCCCCTCACAGGTCACATCTGAGCCTTAGCACCTCCCTCCAAGGGA
CCTGAGCAGGGGACGGGGAGGGGGTTGTCAAATGCGTGCTTCAGTGTACGTGTTCATGCCTCAG
ACAGCGGGTGACGCATGACTGATGGGGGTGTTCTCTAACGTGGTGTGAGGAGAACGAGGACTGG
GGTGCTCTTGTGAACTGTGCAGATGCTATCTGTGGGAGGCCCTGGCCTCGCTGCCGGCATCATG
TATGGCATCACGTACCGTGTTTTACAAACACACTCAGCAGCTGTCCCCATGCAATGGTACTTAG
AGCCCCACACAGCCCAAAGAGCTTGTCCTTGCCTCCCATACCTGTGAGCAGAGGGGACAGGCCA
AGAAGGTGGGTGGCGTCTCTGCTCCCCAACCTTGGGTTGTTCCCAGCGCCTCTGCTGCCCACCC
CCTTGGGTCCCATACTCTCAGGGGAAAGGCCCACGGCCCTTGGTGTGCCCAGGGAGTGCTATGC
AGGGGCCGGAGGGAACCAGCCTACTGCTCTGGCCGCTGGCGTCACTGGGAAACTCTAGAAGGAG
CTGCTGTATGGTCAAGTGATAAAACTTGGAACTCCAACTGCTGGCCCCAGTACTGGGTAATCTC
TAAGTGGGCTGCTGGGCAGGCAAGACCCTTCCTGGTTCTTTTGAGAACCCAGAATGTTGAGGTA
TGTGGGCCCACACAAGGTGGGAGCCAAGTCAGAGAGTCCCAGTCAAATCTGTATCAGGACAGTT
TAGCCACCTCTGAAATAAGCAATAAGTAAGAGTTCCTGGAGTCTGAAGACCAGTCAAGAAAGAG
CCTAGAAACAACCTTTCCCTTTTGGAGAGGTGTGACCCTGTCCCTAATGCTGCAGAGGCATCCT
GGGAACCTAAAGAGAATTTCTTGTAGACCCTCTGCCCTTGTGCAGGGTGGAACAAGATATACCC
CAGCCCTTTGCAGTGGGCTGCCCTCTAGGACAGTCTGCATCATATCTCGAGCCTATCAGGAGAG
GCCAGCAGCACCCAGCGGAGCCCTGGGCTGGGGACCACAGGTGACCTTCGTGACCCCTCCCTTC
CGGAGCCTTAGCTTTGCAGTGCCGACTCTCCATCTCACAGGATGCTTGGACTGGCTCCACCCCC
CACTGTGACAGGTCACCTGGCCCCATCTAGGTGGCCTGGCCTTCCCTGGAGTCAGAATCTGCTG
AGCACATCTTCATCTGCATTCAACAGCCACTCGCCAGTGTTTAAAGACAAAGTGACCTTTCATT
TTTCTTTCTTGAAACTTGAGAGGAAGTGAGATACACACTACTGATTTTTTTTTTTTTTTAAAGA
AACAAACTAGACGCATGGCTGCAGAGTGGCAGAGGTGTCTATTTTCATACTGTGGGGGAAAGTG
CTGCTTTTGGGAGGGGCTGGAACGCCTGGTTTCTGCCCCGGGCCAGTCTTGTACAGGAGTTGGT
GGTGAGCCCTGCAGCTGCCCTCTCCTGCCCTGGCTGTGTAGAGCTGGAGCCTGTGCCCTTCGGC
GGTTTCTACCTTCTATCGAGCCACTTCGATTTGTGGAGAGAGAGAAAAAAATAGAACTTTTGAT
AGTGTGGTAAAAGCATTGATTTGAACTATTTTAGTAAAAGGAGTAACATATAAGACTGTGACAG
TGTCTACTTTGAACTAGATAATAAAGGCCTCTTTGTGAGCCTCGGA

hide sequence

RefSeq Acc Id:

XM_039113371 ⟹ XP_038969299

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	132,877,851 - 132,948,744 (-)	NCBI
mRatBN7.2	6	127,113,440 - 127,184,328 (-)	NCBI

RefSeq Acc Id:

XM_039113372 ⟹ XP_038969300

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	132,877,851 - 132,948,741 (-)	NCBI
mRatBN7.2	6	127,113,440 - 127,184,325 (-)	NCBI

RefSeq Acc Id:

XM_039113373 ⟹ XP_038969301

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	132,877,851 - 132,948,743 (-)	NCBI
mRatBN7.2	6	127,113,440 - 127,184,326 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_006240615	(Get FASTA)	NCBI Sequence Viewer
	XP_038969299	(Get FASTA)	NCBI Sequence Viewer
	XP_038969300	(Get FASTA)	NCBI Sequence Viewer
	XP_038969301	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000076803
	ENSRNOP00000076803.1
	ENSRNOP00000093459
	ENSRNOP00000093459.1

RefSeq Acc Id:	XP_006240615 ⟸ XM_006240553
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5YBH3 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAKPPAVAAAAAAAASEELSQVPDEELLRWSKEELARRLRRAEGEKVGLMLEHGGLMRDVNRRL QQHLLEIRGLKDVNQRLQDDNQELRELCCFHVPPALLPPGPHKGPEGKAGATRRSLDDLSAPPH HRSIPNGLHDPSSTYIRPLETKVKLLDGDKLPPQLPRPYGLQRSRLQQAGSGEFRTLRKGFSPY HSESQLASLPPSYQEVLQNGPACPVPELPSPPSTVYSSAGQKPEAVVHAMKVLEVHENLDRQLQ DSCEEDLSEKEKAIVREMCNVVWRKLGDAASTKPSIRQHLSGNQFKGPL hide sequence

RefSeq Acc Id:	XP_038969299 ⟸ XM_039113371
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038969301 ⟸ XM_039113373
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038969300 ⟸ XM_039113372
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6GKA8 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000076803 ⟸ ENSRNOT00000095434

RefSeq Acc Id:

ENSRNOP00000093459 ⟸ ENSRNOT00000104756

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1589818	AgrOrtholog
BioCyc Gene	G2FUF-36308	BioCyc
Ensembl Genes	ENSRNOG00000065213	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000095434.1	UniProtKB/TrEMBL
	ENSRNOT00000104756.1	UniProtKB/TrEMBL
InterPro	CCDC85	UniProtKB/TrEMBL
NCBI Gene	690965	ENTREZGENE
PANTHER	COILED-COIL DOMAIN-CONTAINING PROTEIN 85C	UniProtKB/TrEMBL
	PTHR13546	UniProtKB/TrEMBL
Pfam	CCDC85	UniProtKB/TrEMBL
PhenoGen	Ccdc85c	PhenoGen
RatGTEx	ENSRNOG00000065213	RatGTEx
UniProt	A0A8I5YBH3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GKA8	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2022-06-02	Ccdc85c	coiled-coil domain containing 85C	Ccdc85c	coiled-coil domain containing 85C	Data merged from RGD:149736150	737654	PROVISIONAL
2021-08-09	Ccdc85c	coiled-coil domain containing 85C			Symbol and Name status set to provisional	45752	PROVISIONAL
2010-04-23	Ccdc85c	coiled-coil domain containing 85C	LOC690965	similar to CG17265-PA	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-01-09	LOC690965	similar to CG17265-PA	LOC684166	similar to CG17265-PA	Data merged from RGD:1593889	1643240	APPROVED
2006-11-20	LOC690965	similar to CG17265-PA			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-20	LOC684166	similar to CG17265-PA			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Mammalian Phenotype

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Imported Disease Annotations - ClinVar

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